Chromatography Forum

Can any body share the procedure to calibrate/to check the performance of Refractive index detector.

Thanks in advance
Bhaskar

To calibrate an RI detector, I have performed precision, linearity, and baseline noise. Precision of six injections of the same solution. Linearity of 5 solutions diluted from the precision solution that cover the range of response generally used in the RI methods. Baseline noise over a 5 minute period, e.g. average of all of the difference of max and min response every 30 seconds for 5 minutes.