rrf calculation

[martinamarie]

Can you calculate rrf from the slope of the impurity / the slope from six injections of the active at 100 % impurity level (ie single point calibration)
Thanks Martina
Can someone clarify this point

[tom jupille]

In principle, yes. In practice, you must have established that the calibration line for both compounds do, in fact, go through zero (but that is a requirement for *any* single-point calibration!).