Chromatography Forum

G'day all!!

I have a couple of questions regarding the types of solvents suitable for GC injection. What makes a solvent suitable for injection? Also, I have read recently about ionic liquids which have no vapor pressure and have been used as GC stationary phases (higher temp ionic liquids), would it be possible for these to be injected into a GC system?

Thanks all in advance!!!

Tristan

you need to define the scope of your analysis.
what are you trying to analize?

I was just wondering if there was any general atributes, such as boiling point, vapor pressure, etc, a solvent had to have to make it usable for GC. As far as the ionic liquids go I have seen literature where they have been used in LLE and then analysed using HPLC and I was wondering if it would be possible to do a similar thing with GC.

Thanks

Tristan

In general it is not advisable to deposit ionic materials onto a GC column as one may change the alpha factor, the selectivity of the column.

Whether this material be solid like sodium chloride, or liquid, possibly irreversible changes to the column may occur. This is exacerbated when using capillary columns.

A good rule to follow for HPLC or GC is never place anything onto a column that does not elute eventually from the column, or that may damage or chemically modify the phase or support, unless that change is intended.

Rodney George

Supelco
595 North Harrison Road
Bellefonte, PA 16823

rgeorge @ sial.com