ammonium acetate buffer

[jiang295]

I used to use HCl to adjust ammonium acetate buffer to ph5 for lcms mobile phase, but it will form ammonium chloride salt, which is very non-volitile.
is it a problem for lcms. should i just use acetic acid to adjust ph?

[tom jupille]

I think you answered your own question.

[jiang295]

so I was doing the wrong thing last year. damn .

I think you answered your own question.