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ammonium acetate buffer

Posted: Mon Mar 29, 2010 3:25 pm
by jiang295
I used to use HCl to adjust ammonium acetate buffer to ph5 for lcms mobile phase, but it will form ammonium chloride salt, which is very non-volitile.
is it a problem for lcms. should i just use acetic acid to adjust ph?

Posted: Mon Mar 29, 2010 6:41 pm
by tom jupille
I think you answered your own question. :wink:

Posted: Mon Mar 29, 2010 6:43 pm
by jiang295
so I was doing the wrong thing last year. damn .
I think you answered your own question. :wink: