Advertisement

Agilent 1200 RID problem

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

4 posts Page 1 of 1
We got the Agilent 1200 RID. Work good for long time. Now, the peaks is too small. Height of peak drop to 500, normally is the 3000. We run sample on other RID. Peaks is good. We check the ALS and pump using VWD. Pump and ALS is good. Problem with RID. Know anyone what this might be? Baseline no is good also. We go to try the big rinse.

Mojo,

We are not mind readers, a description of the chromatography conditions and example chromatograms will get you the quickest advice.
Good judgment comes from bad experience, and a lot of that comes from bad judgment.

Monitor the RID's temp... is it as steady as you're used to?
Thanks,
DR
Image

What about baseline noise? Is it same or higher?
Which mobile phase you use?
4 posts Page 1 of 1

Who is online

In total there are 24 users online :: 0 registered, 0 hidden and 24 guests (based on users active over the past 5 minutes)
Most users ever online was 4374 on Fri Oct 03, 2025 12:41 am

Users browsing this forum: No registered users and 24 guests

Latest Blog Posts from Separation Science

Separation Science offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for users of liquid chromatography, gas chromatography, mass spectrometry, sample preparation and related analytical techniques.

Subscribe to our eNewsletter with daily, weekly or monthly updates: Food & Beverage, Environmental, (Bio)Pharmaceutical, Bioclinical, Liquid Chromatography, Gas Chromatography and Mass Spectrometry.

Liquid Chromatography

Gas Chromatography

Mass Spectrometry