Moisture Content of Mannich Base

[Chandresh K. Soni]

Can Anyone help me or suggest me about the Mannich Base Moisture Analysis.
How we can detect the Moisture Present in the Mannich base. Mannich Base Having the C=O Functional Group Due to this is not Possible on MeOH. and Due to Higher Basicity ( pH 11-12) it was Not Suitable for K.F..

Has Anyone have the Idea for Determination of Moisture in Mannich Base

[Don_Hilton]

Is GC analysis a possibility? Depending on the range of interest I might use GC-TCD raher than GC-MS.

[Chandresh K. Soni]

thank ,
But we dosen't have TCD. and also we want to go for quick analysis on quantitative basis. and gc will take more time as compared to Karl Fischer.

[Don_Hilton]

If KF won't work, as indicated in your original post, then I can only offer an altertantive to KF. And, difficult analyses may take more time and effort. (GC analysis for water can provide exelent quantitation and can have a cycle time of a few minutes.)

If you need an alterative KF reagent - talk to your vendor for KF reagents.