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Front CID fragmentation mechanism

http://www.chromforum.org/viewtopic.php?t=12334

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Front CID fragmentation mechanism

Posted: Tue Feb 23, 2010 2:03 am
by ym3142
Hi

a thiazole moiety has 98 mass unit. But in "front CID" when it was cleaved out of the mother molecule I found a ion of 100 mass unit. I do not understand the mechanism.

Any one knows some good reference about CID fragmentation?

Thanks in advance

Posted: Wed Feb 24, 2010 10:38 am
by ym3142
I guess the answer is more simpler than I thought: one mass from a protonation(to become detectable cation) and the other from obtaining a proton after the covalent bond cleavage.

Please let me know this is wrong.

Posted: Wed Feb 24, 2010 10:39 am
by ym3142
oops, "please let me know if this is wrong"
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