Front CID fragmentation mechanism

[ym3142]

Hi

a thiazole moiety has 98 mass unit. But in "front CID" when it was cleaved out of the mother molecule I found a ion of 100 mass unit. I do not understand the mechanism.

Any one knows some good reference about CID fragmentation?

Thanks in advance

[ym3142]

I guess the answer is more simpler than I thought: one mass from a protonation(to become detectable cation) and the other from obtaining a proton after the covalent bond cleavage.

Please let me know this is wrong.

[ym3142]

oops, "please let me know if this is wrong"