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Need sughgestions for replacing old HPLC pumps

Posted: Tue Aug 05, 2025 7:25 pm
by cigtoxdoc
I have a small laboratory that supports my consulting business by checking clients' samples before sending them to an ISO 17025 accredited lab. I have been using Waters 510 pumps that I purchased on eBay some years ago. The electronics side of these pumps are failing, and I need to get some new pumps. All my separations are isocratic and use acetonitrile/water for the mobile phase. Nothing exotic, but output of pumps needs to be smooth enough not to show on my RI and DAD detectors.

Suggestions and offers of new pumps more than welcome.

Thank you,

John

Re: Need sughgestions for replacing old HPLC pumps

Posted: Wed Aug 06, 2025 1:19 pm
by Consumer Products Guy
I would expect all modern HPLC pumps would perform better than pumps from an earlier era.

Re: Need sughgestions for replacing old HPLC pumps

Posted: Wed Aug 06, 2025 1:54 pm
by DR
Go back to ebay and find a similarly designed pump with working electronics and continued parts availability.
I suspect there are Shimadzu, Milton Roy, Knauer and other options available...

That said, and with all due respect to you and your lab, I am amazed that there's a business model supporting people who distrust ISO accredited labs enough to send samples to your little lab based on ebay purchases!

Pointy haired bosses - still out there.

Re: Need sughgestions for replacing old HPLC pumps

Posted: Thu Aug 07, 2025 6:38 pm
by cigtoxdoc
Thank you for your reply. When my clients have lab work done, I serve as sponsor's rep, and a key part of that job is reviewing the labs methods, QA systems and the preliminary results. Also, my clients don't have labs, so I always make sure that what they plan on sending to the analytical labs is what they intend to send.

John

Re: Need sughgestions for replacing old HPLC pumps

Posted: Fri Aug 08, 2025 11:50 am
by elsico
Good choice to buy something like used Waters 515 or Gilson 307.
Good luck to you and your lab)