Chromatography Forum

Hallo,
I would like to know if there is anyone who knows studies of the deconvolution of peak pairs and either their calibration or studies on the degree of overlapping of two peaks. It was not impossible for me to make a precise research and find articles exactly corresponding to this subject. Searching with the key words overlap, Gaussian peak and height I found by chance one article for each point, but I looked only at 100 publications of over 46500 articles dealing in some way with peak deconvolution, Gaussian peaks etc. in many other ways.

Can anyone help me?

Sincerely

Thomas

Thomas,

Have you looked at the work of Dr Rob Synovec at University of Washington? He has done extensive work in the area of chemometrics and in the process I am sure he has looked at the issues you describe. I do know it was one of his grad students that looking at peak shapd and height as they affected calibration since i attended one of her presentations.

Good luck and Best regards,

AICMM

like in your previous thread, maybe have a look at

Tom O'Haver, Professor Emeritus, Department of Chemistry and Biochemistry, University of Maryland:
"A Pragmatic* Introduction to Signal Processing - with applications in scientific measurement:
An illustrated essay with free software and spreadsheet templates to download"

https://terpconnect.umd.edu/~toh/spectrum/TOC.html

He also have a section about deconvolution.


Another source focused on chromatography could be the book by Kromidas and Kuss
in German:
"Chromatogramme richtig integrieren und bewerten
Ein Praxishandbuch für die HPLC und GC"
Kromidas, Stavros / Kuss, Hans -Joachim (Herausgeber)
1. Auflage März 2008
XVIII, 402 Seiten, Hardcover
160 Abbildungen (8 Farbabbildungen)
85 Tabellen
Praktikerbuch
ISBN: 978-3-527-31774-5
Wiley-VCH, Weinheim

or in English (I guess it's the same but translated)
"Quantification in LC and GC. A practical guide to good chromatographic data"
Hans-Joachim Kuss and Stavros Kromidas (eds.)
Wiley-VCH
ISBN: 978-3-527-32301-2
Hardcover, 376 pages, September 2009

Thanks very much for this hint. Great web site! I will have a thourogh look at such pdf files!

Thommy7571