Random Large Peak Popping up Unpredictably
Posted: Mon Feb 24, 2025 7:16 pm
I'm having a very strange (to me) issue and don't know how to find the solution.
On one of my GCs, only one of them, a very large peak (very tall, skinny, and takes up 99% of the total peak area) is popping up *sometimes*
It's only that one, and it's not every run. I can have it pop up and then run the exact same sample again and it won't be there. Nothing has changed. To make it worse, it doesn't even elute at the same times every time
I've seen it at 4 mins, 25 mins, and 18 mins.... again same GC, column, and method/settings.
All other peaks look normal, and when I delete that one concentrations of other peaks return to normal.
Anyone have a suggestion on how to approach this?
On one of my GCs, only one of them, a very large peak (very tall, skinny, and takes up 99% of the total peak area) is popping up *sometimes*
It's only that one, and it's not every run. I can have it pop up and then run the exact same sample again and it won't be there. Nothing has changed. To make it worse, it doesn't even elute at the same times every time
I've seen it at 4 mins, 25 mins, and 18 mins.... again same GC, column, and method/settings.All other peaks look normal, and when I delete that one concentrations of other peaks return to normal.
Anyone have a suggestion on how to approach this?