The chance that the degasser connection "tubing" in your Dionex/Thermo Quat Pump (not the membrane tubing) is the reason for the failure is very close to zero (sure, it is
possible that a section of tubing has come loose, but we have never seen such a thing on a LPG module, ever). These modules wear out from use and a "normal" lifetime, if used daily, is four years. By the time any error message appears, the system has significant damage inside and has contaminated the entire flow path of your HPLC system (if you have a MS, then the source too may be contaminated). You should budget to have the integrated degasser module replaced at that interval (delay equals more damage and often higher repair cost plus invalid data). If you use your HPLC to perform a "service" or work in a regulated environment, then the HPLC is out-of compliance when the degasser is not serviced. Have them all serviced regularly. Professional testing equipment and knowledge are required to test these modules, out of the pump, on the bench. Even Thermo does not have this equipment of test them this way (waste of time and money for both them and you). Replacement of individual component parts (w/o professional testing of the component parts) is also a sure way to waste money too. Standard procedure for the vendor involves replacement of: the tubing, vacuum pump/PCB frame module and the 4-vacuum channels to insure that you start off with a clean, functional system. If you just replace the tubing, then the replacement tubing will be quickly contaminated by the system (so you will need to remove it again and place it in the trash). If you replace only the vacuum pump ( a newbie mistake, do not doe this), w/o finding out WHY it failed, then the replacement vacuum pump will be contaminated by the debris inside the tubing, chambers and sensor. Replacing all four chambers alone, again, will subject them to contamination from the tubing and vacuum pump. We have see so many people make these mistakes over and over. The vendor makes extra money selling the client the individual parts, then finally the whole degasser module (so customer pays 2x or more). Save yourself money, replace the whole degasser module (Please be careful Thermo does not give you a quote for just the vac pump and call it "The degasser") and get back to work. Again, this is a normal wear-and-tear part so should be budgeted.
For users in the USA, you can send the integrated vacuum degasser module (The internal 'L' frame with the Vacuum pump and PCB, the vacuum tubing and all of the vacuum chambers) to Chiralizer Services, LLC (USA) for inexpensive professional testing and optional repair service. This allows you to have the complete module serviced at a much lower price (you will save several thousand dollars) since any components that can be cleaned and re-used/repaired need not be replaced.
To answer your question about the LPG degasser connection tubing: Their are three different versions of the integrated degassers used in the Thermo/Dionex LPG pumps. Each one uses completely different parts/designs, which are not interchangeable, so it would have to be seen to know which one is in your pump. However, all of them use cheap silicone lab grade tubing for the degasser connection tubing as std (for HPLC use, not LC-MS). The vacuum chamber degassing membrane tubing/film is different, for the different variations and not available for sale to end-users.
Dionex / Thermo integrated Degasser Repair Services Link:
https://www.hplctools.com/degasser_malf ... rvice.html
