HPLC/PDA advantages over GC/MS

[offroad]

Dear friends...

What are the advantages of an HPLC/PDA compared to a GC/MS?

If I already have a GC/MS/FID/TCD, what would make me buy an HPLC/PDA/RI?

Thank you

[grzesiek]

What if the stuff you want to analyse is not volatile?

[offroad]

yes, of course, but.... besides the obvious, I thought it had something to do with the fact that some compounds are poorly identified by a GC/MS and then a HPLC/PDA would fit better. I don't know, maybe the analyte needs a much longer column to separate into simple compounds etc.

Anyways, thank you.

[tom jupille]

Not much beyond the obvious. HPLC developed partly in response to the fact that most organic compounds are not sufficiently volatile/thermally stable to be done by GC.