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two compounds eluting at same time

Posted: Tue Oct 27, 2009 8:29 pm
by che313
who to separate two compounds eluting at same time even if they dervatized??

Posted: Tue Oct 27, 2009 11:19 pm
by Ron
Use a different column.

Re: two compounds eluting at same time

Posted: Tue Oct 27, 2009 11:41 pm
by Peggsy
who to separate two compounds eluting at same time even if they dervatized??

seems as though not you!

Posted: Thu Oct 29, 2009 9:40 am
by grzesiek
"seems as though not you!" :)

"Use a different column." - probably the best guess with so much info that is provided :(

Posted: Tue Nov 03, 2009 2:30 pm
by SkylineGTR112
1.) Temperature Change
2.) Tweak Flow settings
3.) Different Column

What are the compounds you are trying to separate?

Posted: Wed Nov 04, 2009 10:04 am
by orcicdejan
MS might be useful if they have different ions, just use SIM. However, keep in mind that (if the concentrations are high) some interferences are possible (suppression of ionization...), but even that can be solved by standard addition method.