calculating polarity of a compound

[vishall79]

How to calculate polarity of a compound from the structure?

[danko]

The universally accepted approach is: Do some of the work yourself (search and read relevant material). If one – following the initial phase – needs some help or ideas or whatever, then ask people on this or another forum, or maybe some colleagues, or friends etc.
If I remember correctly, the topic was up on this very forum, a few days ago.
Just asking the shortest possible question won’t bring you far.

Best Regards

[tom jupille]

To elaborate on danko's response: some idea of your context would be helpful: what aspect of "polarity" are you interested in and what are you going to do with the information?

[Chromatographer2010]

There are some modeling tools available on the web for calculating polar surface area which has been shown in some cases to correlate to retention on reversed phase columns.

http://www.daylight.com/meetings/emug00/Ertl/index.html

Is one example.