two compounds eluting at same time

[che313]

who to separate two compounds eluting at same time even if they dervatized??

[Ron]

Use a different column.

[Peggsy]

who to separate two compounds eluting at same time even if they dervatized??

seems as though not you!

[grzesiek]

"seems as though not you!"

"Use a different column." - probably the best guess with so much info that is provided

[SkylineGTR112]

1.) Temperature Change
2.) Tweak Flow settings
3.) Different Column

What are the compounds you are trying to separate?

[orcicdejan]

MS might be useful if they have different ions, just use SIM. However, keep in mind that (if the concentrations are high) some interferences are possible (suppression of ionization...), but even that can be solved by standard addition method.