Chromatography Forum

Hi all

have any of you tried doing Accurate mass measurements using APCI as ionization technique?
if so what reference compound works?
i've tried PEI, sodium TFA (not great I know) and PEG.
PEI seems to give the best signal but lacks reference peaks in the low mass range...

any ideas would be appreciated

kind regards

MassSpecM,

I know Agilent sells a tune mix for APCI (but I have no direct experience with it).

http://www.chem.agilent.com/Library/msd ... nglish.pdf


Best regards,

thanks a lot!

i'll try this and give feedback!

MassSpecM,

I know Agilent sells a tune mix for APCI (but I have no direct experience with it).

http://www.chem.agilent.com/Library/msd ... nglish.pdf


Best regards,

Yes this is the same standard solution you can use with ESI source.
Dilute it 1:10 with ACN and inject it.
The conc. solution is quite stable, you can store it at room temp without any degradation. The diluted one is better preserved at 4°C.