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Postcolumn infusion for evaluation of the matrix effect

http://www.chromforum.org/viewtopic.php?t=11383

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Postcolumn infusion for evaluation of the matrix effect

Posted: Sun Sep 27, 2009 6:16 am
by gxch43
hello.
Postcolumn infusion experiments usually were used for the evaluation of the matrix effect, Should I run a blank solvent sample first
and subtract the blank solvent peaks from the blank matrix peaks to evaluate the matrix effect ?

Posted: Sun Sep 27, 2009 12:50 pm
by Kostas Petritis
I do not exactly what set-up you use exactly post-column but if you have solvent peaks that create ion-suppression it is useful information that you should use during method development...
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