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Separation of D & L phenylephrin

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

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Separation of D & L phenylephrin

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Chandresh K. Soni
how i can Analyze D & L phenylephrin in Reverse phase Chromatography without using Chiral Column on UV Detector. I Have the C-8 , C-18 , Cyano Column For The Analysis.

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Uwe Neue
To separate D/L isomers, you either need chiral additives to the mobile phase or a chiral stationary phase.

The enterprise to do it with additives in the mobile phase is not trivial, and you will be better off taking a pre-cooked method from the literature or from a manufacturer of chiral stationary phases.
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