analytical method development difficulty
Posted: Wed Aug 12, 2009 2:11 pm
by subathrai
am developing a uv and rp hplc method for the triple combination glimepride (2 mg)+rosiglitazone (2mg)+metformin (500 mg) tablets. it is quite difficult with this wide range of label claim. plz suggest me any ideas to develop a method in this combination.
Posted: Wed Aug 12, 2009 5:42 pm
by grzesiek
"Simultaneous estimation of metformin hydrochloride, pioglitazone hydrochloride, and glimepiride by RP-HPLC in tablet formulation."
"Simultaneous determination of metformin and glimepiride in pharmaceutical dosage form by reverse-phase liquid chromatography."
this were found in google, maybe it'll be helpful
Posted: Wed Aug 12, 2009 5:47 pm
by subathrai
thanks grzesiek