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Chromatography Forum

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Discussions about GC-MS, LC-MS, LC-FTIR, and other "coupled" analytical techniques.

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shahis77
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Last edited by shahis77 on Mon Aug 24, 2009 10:27 pm, edited 1 time in total.

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MaryCarson
Do you know whether your parent compounds even elutes with your mobile phase conditions? The parent is quite likely more hydrophobic than its oxo metabolite. If you need 90% MeOH to bring the metabolite off a C18 column, maybe you should try a C8?
All standard disclaimers apply. My posts are my opinions only and do not necessarily reflect the policies of my employer.
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