HELP GCMS Sensitivity Problems Shimadzu

[LWC]

Hello,

I have a Shimadzu QP 5000 and recently we had an air leak that lead to several issues. I have cleaned the MS and replaced all of the parts of my injector and trimmed the column a bit on the injector side. My tunes look good and my pressure is steady however I cannot get my sensitivity back to where it once was. Is this a column issue? What do you think?

Thanks

[Consumer Products Guy]

Try with a manual injection, different syringe.

[LWC]

[quote="Consumer Products Guy"]Try with a manual injection, different syringe.[/quote]

I have, no difference, sorry forgot to include that.

[Ron]

What is the condition of the filaments? Have you tried switching to the second filament to see if the response is better? The QP-5000 has a ribbon filament instead of a wire, and if the filament warps or wrinkles the sensitivity can be affected.

[LWC]

[quote="Ron"]What is the condition of the filaments? Have you tried switching to the second filament to see if the response is better? The QP-5000 has a ribbon filament instead of a wire, and if the filament warps or wrinkles the sensitivity can be affected.[/quote]


The filaments were new in MArch and switching them doesn't seem to make a difference. Talking to another guy from Shimadzu he lthinks it could be a ferrule issue in the inlet or and electrical phenomenon?

[AICMM]

LWC,

Being that one of the last things you did was trim the column, are you sure you got the column position in the inlet correct? Can make a huge difference in sensitivity. Split or splitless and what kind of liner?

Best regards.