The method is intended for the highly selective determination of six antihistamine drugs (cetirizine, chloropyramine, chlorpheniramine, pheniramine, desloratadine, doxylamine) in various pharmaceutical and biological samples using simple isocratic 400 bar HPLC system with a conventional UV detector.
The method is capable to determine antihistamines in complex matrices that contain any neutral or acidic matrix compounds, as well as various basic compounds like drotaverine, dextromethorphan, phenylephrine, etc.
The method is not capable of determining loratadine.

The aim of this project is to provide our customers with reasonably priced (25-100$), state-of-the-art HPLC approaches that can be used to develop the most cost-effective commercial HPLC methods easily and quickly. All methods can be downloaded from our web-site