Oxidation using Oasis WCX cartridges
Posted: Fri Jan 24, 2020 1:06 pm
It is a little surealistic to google a problem, and find that I asked the very same question in this forum in 2006...
Anyhow, I have a problem with oxidation when using the Oasis SPE products. The results are very clear, when using the Oasis WCX cartidges I get up to 100% oxidation of my peptide.
When I changed to a silicabased SPE cartridge (Strata WCX) I see no oxidation at all. Waters says that there are no oxidising substances in the Oasis material, but that is obviously not true.
Anyone else that has seen this phenomenon?
Anyhow, I have a problem with oxidation when using the Oasis SPE products. The results are very clear, when using the Oasis WCX cartidges I get up to 100% oxidation of my peptide.
When I changed to a silicabased SPE cartridge (Strata WCX) I see no oxidation at all. Waters says that there are no oxidising substances in the Oasis material, but that is obviously not true.
Anyone else that has seen this phenomenon?