Best pratice for Related substances intergration
Posted: Mon Oct 28, 2019 10:50 pm
Hello
Just wondering what "best practice" for integration would be :
In related substances is it acceptable to set a minimum arena in any circumstance (for example 5 times less then your LOD) to remove unwanted base line noise.
I've always had the opinion that you should essentially integrate everything (except minor baseline fluctuations ) and then let the CDS use the sensitivity injection to disregard anything below LOQ
Just wondering what "best practice" for integration would be :
In related substances is it acceptable to set a minimum arena in any circumstance (for example 5 times less then your LOD) to remove unwanted base line noise.
I've always had the opinion that you should essentially integrate everything (except minor baseline fluctuations ) and then let the CDS use the sensitivity injection to disregard anything below LOQ