I understand some folks being skeptical. I think the manufactures of Primesep have done a great job on their website explaining the technology. The good thing is that anyone can visit the website and check it out for FREE, unlike some other column manufacturer websites where you need to sign in and give up your life history just to take a look at the latest column technology, which once you read about it, you discover that it the same old column with a fancy new name!
If you are an accomplished chromatographer than it is very easy to see for yourself. Simply read the material, access the proper Primesep column and design some simple experiments. Have you got an old method that you developed that was difficult? Maybe you were forced to use an ion pair reagent, or develop 2 methods instead of one. Or you had to do a long gradient? Maybe you got the method, but one of your components is coming out 0.02 seconds past the void. Or maybe you have tailing amines? Rework these old methods with the new technology. Also there are several published methods that use ion pair that you can check out (USP, etc...) Again, if you are an accomplished chromatographer you can check this out in very short time in your own lab.
The best data is the data you obtain yourself. Don't be lazy and expect someone to hand you a book with all your methods worked out. No matter what is published (or writtten on a forum), some folks will always be skeptical, and need to establish their own data. That's what I did, and I am sold on this technology.
My lab has DOZENS of columns that I have bought that are absolutely worthless. Each one claimed to be able to do something, and it was nothing more than a waste of time. Some of those columns have already been mentioned in this thread.
Everyone does different work, and no claim was ever made to say this column will do everything, as no column can do that. I am amazed how some folks just go out sniping, trying to find some application that doesn't apply! I laughed at that one! How childish!
In my work, I have desired such column technology for years. Finally it is here and after checking it out, it found it fills a large void in my arsenal of columns. I have real problems that the column technology solves and like most of my work, due to the propriatary nature I will never get to publish or talk about it outside of my lab.
As I said above, time will tell. Yes, scientist are skeptical, but good scientists don't sit around waiting for the journals and symposia to publish mountains of data, they check it out for themselves.
