Normal phase LC

[chhubert]

Dear all,
Wondering if I need to change the pump seal when I switch my Waters 600E pump from reverse phase LC operation to normal LC. Apparently there are heaps of different pump seals available but they look similar. Thanks for your suggestion.
Hubert

[tom jupille]

I would check with Waters. The standard seals are "general purpose" and can be used with a wide range of solvents, but there are some compatibility issues.