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- Posts: 6
- Joined: Wed May 24, 2023 12:37 pm
- Location: Germany
I have been working with food matrices for a while using LCMS to quantify targeted pesticides and contaminants. For confirmations we regularly use standard addition (with only 1 level due to needing to save time).
My information has always been that it is recommended to add to the sample at least 2x what the initial concentration approximation is. Can anyone explain to me why this is and how/when it works better than adding the same amount as is seen in the sample?
They do not do the same in GC, is there a reason for this?
My information has always been that it is recommended to add to the sample at least 2x what the initial concentration approximation is. Can anyone explain to me why this is and how/when it works better than adding the same amount as is seen in the sample?
They do not do the same in GC, is there a reason for this?
