PEEK UPLC needle and DMSO

[aceto_81]

Hi,

does anyone know wether an PEEK UPLC needle can be used to inject a solvent mixture of 20%DMSO in water?
I know DMSO may cause swelling of PEEK, but what about 20% DMSO in water?


Kind regards

Ace

[zokitano]

I know that PEEK columns (monolith columns) shouldn't be used with more than 5% DMSO, 5% methylene chloride and more than 50% THF in the mobile phase.

But when it comes to PEEK needle I am not sure. Just for security I would suggest you to stick to the given (previously) limits for the solvents when using everything that is made of PEEK (columns, tubings, needles)

Hope this helps,
Regards

[Steph5217]

It exist steel needle for UPLC. It may be the best solution for you.

[aceto_81]

Thank you for coming up with the SS needle, but I already knew about the SS needle, but I think it's not feasable to always change the needle for 1 method, while the other methods are using PEEK needles.

Ace