Static-Headspace extraction questions

[Hyunsu]

Hi, I am recently trying to analyze some volatile compounds by static-headspace GC-MS.

I made standard stock solution using HPLC grade water.

What if I increase equilibration temperature above 100℃ (water boiling point)?

Is it okay to increase the temperature till 85℃, while using water as solvent?

I think it is not appropriate to increase the temperature because of water boiling point, however, my target compound's boiling point is way higher than water's boiling point.

[Peter Apps]

Welcome to the forum

What kind of headspace sampler are you using, and what is the boiling point of your target analyte ? If it's boiling point really is way above that of water it may more be suitable for heaspace analysis.

Peter

[ingochrist]

As long as you analytes evaporate, you don't need to go to their boiling point. My typical HS temperature tends to be 50 - 85C max, otherwise the syringe lasts not very long or you have problems with the solvent, since you over pressurize the vapor phase.

Regards,
Ingo
Autosampler Guys

Hi, I am recently trying to analyze some volatile compounds by static-headspace GC-MS.

I made standard stock solution using HPLC grade water.

What if I increase equilibration temperature above 100℃ (water boiling point)?

Is it okay to increase the temperature till 85℃, while using water as solvent?

I think it is not appropriate to increase the temperature because of water boiling point, however, my target compound's boiling point is way higher than water's boiling point.