Injecting HCl solutions into HPLC

[zvi]

A technical rep here just sent me the following link whereby they inject a sample dissolved in 3/4 of a 0.1 N HCl solution:
http://www.fda.gov/cvm/melamine04022007.htm

[Flappytango]

ZVI,

Rob is correct. 0.1N HCl is very commonly used and injected when performing dissolutions.

just peruse the FDA-Recommended Dissolution Methods which can be found at the below link

http://www.accessdata.fda.gov/scripts/c ... ex.cfm?c=1

[zvi]

Thanks.
Are these HCl solutions also injectable into LC- MS systems and not just HPLC?

[Kostas Petritis]

It's also injectible in LC-MS...

[zvi]

Thanks everyone.