DAD vs. DWD S/N-difference [August 13, 2004]

[admin]

By Confused? on Friday, August 13, 2004 - 04:49 am:

Hey all!

What do you think about a signal to noise ratio (and sensitivity) difference between two detectors, namely DAD (agilent) and DWD (Waters)? DAD gave about 40 times smaller S/N-ratio than DWD. Is it possible even in theory or should we look a reason for this from somewhere else?

[admin]

diode-array detectors are probably somewhat less sensitive than variable-wavelength, but 40X seems a bit much. Are you sure you're running both detectors under equivalent conditions (bandpass, time constant, etc.)?

-- Tom Jupille