Saccharin in water

[hts123]

Do anyone have any idea with how to extract saccharin from water samples using solid phase extraction? I had tried to acidify the water samples to pH 1 then passed through oasis hlb cartridges at 5mL per minute but I could not recover any saccharin!

I appreciate any help from any fellow forum users.

Thank you for reading!

[Consumer Products Guy]

Do anyone have any idea with how to extract saccharin from water samples
I appreciate any help from any fellow forum users.

Why is there need to extract the saccharine? With its structure, should have decent UV absorbance if you're just trying to quantitate the level.

[James_Ball]

Have you tried it at a neutral pH?

I see it sometimes in wastewater samples done by sepfunnel extraction but have never done it by solid phase, though it should work.

Maybe try a plain C18 on silica cartridge also.