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using glycine in mobile phase

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using glycine in mobile phase

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amitavaghosh
generally we are using glycine in mobile phase in related substance method for -zoles(pantoprazole,esomeprazole,lansoprazole,rabeprazole) type compound, what is the reason behind this? what is the role of glycine?

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Jumpshooter
glycine enhances the viscosity of the carrier phase---keeps the 'zoles from having a decreased retention t.
Jumpshooter

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HW Mueller
Jumpshooter, where did you get that?
I have seen glycine used as a buffer and ionic strength modifyer.
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