determine releted substances of arginine by HPLC

[oj]

Hello,

I would like determine releted substances of arginine by HPLC.

Can anybody tell me, the degradation products of arginine and the HPLC method for determine of them.

Thank you.

[Wen Jiang]

HI OJ,
Ther are numerous results can be found on the pathways of arginine degradation by Google search. Detail information are shown in the followed website: http://biocyc.org/META/NEW-IMAGE?object=ARGININE-DEG
Since arginine and its degraded products mostly are polar and hydrophilic compounds, I suggest you try HILIC first. The combination of HILIC and MS will be very unique for your project.

[oj]

Thank you for advice Wen Jiang.