The history of HPLC

[sksrinivas]

Hello all

I'm presenting a lecture on HPLC to post-grad students and I'm trying to get my facts right on the history of HPLC.

There are several websites on the Net of course, but I need an authoritative website or a reference that I can quote with confidence. During my Net search, I came across many contradictions, especially with respect to who developed the first 'real' HPLC instrument.

I'm especially interested in Jack Kirkland's early work. Due acknowledgement will be given, as is always the case in my HPLC lectures.

Thanks in advance!

S.K. Srinivas, MPharm
Chromatography Training

[Uwe Neue]

The question is what you call the first "real" HPLC instrument.

Csaba Horvath had built one very early on. I do not have the reference on hand, but I can find it for you. We had home-made things at the university. Commercial instruments had more than one source. The Waters instrument evolved from their development in GPC, which was MUCH earlier than HPLC.

As far as I am concerned, I define the beginning of true HPLC as the point in time when people figured out how to pack smaller than 30 micron particles. I believe the first publication was by Kirkland in 1972, closely followed by other publications, including one by Ron Majors, if my memmory serves me correctly. Commercial columns packed with 10 micron particles became commercially available in 1973 (microBondapak C18 and microPorasil).

You can either dig out the references yourself, or I can help you, if you contact me.

[Jamie]

L.S. Ettre is into the history of chromatography. One year after the death of Csaba Horvath he published in LC/GC magazine his contribution to HPLC. If you google Csaba Horvath you will come accross this article.

Jaime

[sksrinivas]

Thanks Uwe and Jaime

I've a lot of information now for my lecture. Ettre's articles on chromatography are excellent! Just what my students need.

I do hope I can use them in my lectures, with due acknowledgement.

Whom do I ask for permission?

Srinivas

[Uwe Neue]

I am surprised about your question about permission to use information in a paper in a presentation. I think the citation of the source of the information is all you need. I think that this is different then the use of graphs in subsequent publications. It is definitely different from copying the articles for distribution.

There is only one area that appears to be grey to me: the handouts in courses for which you are paid. If this is the intended use, you can get in touch with the magazine and inquire.