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RID vs ECD for Sugar analysis

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

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Hello,

I am trying to decide on either an RI or EC detector for sugar analysis. Does anyone have experience with either of these?

Thanks in advance.
I have routinely used an RID detector for simple sugar analysis per ICUMSA
(International Commission of Uniform Methods of Sugar Analysis) guidelines. The RID is 'very' prone to interferences (alright for HFCS, jams, jelly beans), it is insensitive (it detects sub%), temperature or pressure changes...
This recent thread discusses RID and sugars. Maybe some info of use to you there:

viewtopic.php?f=1&t=44761
I am trying to decide on either an RI or EC detector for sugar analysis.
1. Relatively high concentration of sugars, relatively simple matrix of sample and isocratic conditions (only) = RID

2. Otherwise = ECD
Many thanks everyone.

I guess ECD is the way to go.

Thanks Jake for the link :)
5 posts Page 1 of 1

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