Response difference between packed and unpacked liner

[MartinP]

I am seeing a 10 fold increase in response when I use an unpacked single tapered liner instead of my usual glass wool packed single tapered liner (SGE Focus Liner). I expected to see some difference but not as much as this. Anyone got an explanation.

Cheers

[GOM]

Martin,

Would you add what the analyte is and its concentration.

Thanks.

[GOM]

oh - and is the solvent peak staying the same width?

Ralph

[Peter Apps]

split or splitless ?

[MartinP]

I am using an in-house test mix containing compounds with a variety of functional groups at concentrations of approx. 0.1% in acetone. Injections are 100:1 split. All compounds are affected equally.

[Peter Apps]

Hi Martin

Like a lot of people posting problems you are making this difficult by supplying information one little piece at a time as if you are a suspect being interrogated !!

Please supply FULL details of your set-up and methods, i.e. column dimensions, flow rates, injection manual or auto etc etc so that a diagnosis does not have to be based on guesswork.

Thanks Peter