anti-oxidant for stabilizing compound?

[dougs]

I have a compound that degrades quite fast from oxidation. The diluant is water. Are there any anti-oxidants I can try to use for stabilization?

Regards
DS

[KarenJ]

Dougs,

We had good luck adding ascorbic acid to a sample solvent for a compound that was easily oxidized. It's a good anti-oxidant, it's non-toxic, and inexpensive.

Karenj

[dougs]

thanks for the info. What kind of concentration may be required? 0.1%? 1%?

Regards

[Bill Tindall]

also there are some thio compounds that are very effective. I don' t have my book at hand right now to look up what they are, but look up methods for low levels of acsorbic acid. They involve adding one of these compounds to prevent oxidation. They are very effective and work for all sorts of oxygen sensitive analyses.

[Mark Tracy]

In addition to ascorbate... Sodium thiosulfate is also useful. People used to use thiodiglycol te preserve samples for amino acid analysis, but that probably was not that effective. Dithiothreitol will keep other thiols in the reduced state. Lowering the pH is effective for some phenolics and thiols. If transition metals are catalyzing the oxidation, you can try EDTA.