2-Fluoro Toluene GC analysis for isomers

[bhaskarac]

Dear All,

I am trying to separate 2-Fluorotoluene from its isomers 3-Fluoro and 4-Fluorotoluenes by GC. But I am unable to get good separation even with 75metres column also(I used AT-Wax).I hardly getting a resolution of 1. But I am unable to get Base to base separation.
Can any body have any experience with these isomers.And can you please share the GC method.

Thanks in advance

[chromatographer1]

difficult separation, yes. But I don't have a solution for you.

Things to try:

Determine if you are running at optimum flow and temperature parameters, lower flow and temperature parameters even lower, just to make sure.

a trifluoropropyl methyl capillary?

a chiral GC column?

a bentone 34 capillary column

gas solid chromatography mechanism

Call a supplier of the isomers and ask them what they use.

Try LC or NMR to achieve purity determination.

Take a vacation and think about it for while.

Good luck and best wishes,

Chromatographer1