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Has anyone tried using Upchurch 2µ inlet solvent filters (catalogue No. 42700-00) for UPLC analysis? Does it cause more backpressure compared to the traditional 10µ HPLC inlet solvent filters?
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Upchurch 2µ inlet solvent filters for UPLC anlaysis
Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.
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Practically , I don't think that 2µ filters produce more backpressure ( actually correct word is more ''vacuum '' ) at the beginning , but certainly they will be clogged more rapidly in the time course.
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The frits at the end of the UPLC column would be significantly smaller than 2 micron.
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