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Detection modes for FFF?

http://www.chromforum.org/viewtopic.php?f=1&t=94124

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Detection modes for FFF?

Posted: Wed Feb 27, 2019 11:08 am
by sethlyn
Which detection modes are appropriate for use with FFF?

Re: Detection modes for FFF?

Posted: Wed Feb 27, 2019 11:09 am
by DanSome
Most types of online detection that are used for macromolecules and nanoparticles are appropriate for FFF: UV or refractive index to determine concentration and retention volume; multi-angle light scattering (MALS) to determine molar mass and rms radius; dynamic light scattering (DLS) to determine hydrodynamic radius; fluorescence to identify composition or concentration; and even mass spectrometry such as ICP-MS to determine elemental composition or size single particles consisting of single elements.
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