Size for MALS

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

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I'd like to know what is the largest size quantifiable by MALS?
The largest size that can accurately be measured by light scattering depends on the number of angles used to measure the sample. The Wyatt DAWN has 18 angles of detection which is sufficient to measure samples up to 1 µm in size.

[answer provided by Mark Spears, Ph.D., Fujifilm Diosynth Biotechnologies]
Daniel Some, Ph.D.
Principal Scientist
Wyatt Technology Corp.
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