-
- Posts: 5329
- Joined: Thu Oct 13, 2005 2:29 pm
- Location: Maun Botswana
In HPLC you have a mechanical pump with wearing parts, in GC you have a gas cylinder. In HPLC you have to make up mobile phase every couple of days, in GC you change a cylinder once a month. In HPLC there are thousands of mobile phase recipes, in GC there are three (and they only affect the speed of the analysis). In GC you have a temperature programme, in HPLC you have mobile phase gradients. There is no HPLC equivalent of an FID (which is both a good and a bad thing). Choosing the right column is more critical in HPLC.
Peter