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Difference between delay and void volume

Posted: Wed Mar 20, 2013 5:25 pm
by GIRI BABU
Whats the difference between the void volume,dead volume,delay volume of column ?how its vary from one column to other?

Re: Difference between delay and void volume

Posted: Thu Mar 21, 2013 2:58 am
by tom jupille

Re: Difference between delay and void volume

Posted: Sun Jul 30, 2017 11:50 am
by aalbre
Hi, I also have one question, which I hope you can help me with. How do you call a volume (or time) which combines the system dwell (delay) volume + column void volume?

My problem is that I don't know how to describe the time in the chromatogram when my baseline actually starts to drift in a gradient analysis (the effluent hits the detector). This is not the hold-up volume since it doesn't take the pump and mixer into account, right?

Cheers
A

Re: Difference between delay and void volume

Posted: Sun Jul 30, 2017 8:58 pm
by tom jupille
As far as I know, that sum does not have an "official" name. I usually just use "tD + t0", but so long as you define your terms, you can call it whatever you want.