COLORIMETRIC TECHNIQUE

Basic questions from students; resources for projects and reports.

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hello,
i would like to know the principle of DSC and what is the use of this direct scanning colorimetry in pharmaceutical industry?

Hi,

You can go through this page then u will know all the details about Differential scanning calorimeter

http://las.perkinelmer.com/content/Rela ... 887_01.pdf

http://www.ms.ornl.gov/htmlhome/tpuc/dsc.html

all the best

Calorimeter specifically for heat capcity measurement.

In pharmaceutical to identify the heat capcity of drug whether it is having endothermic or exothermic nature.

Heat is evolved in exothermic processes and absorbed in endothermic processes; such processes include chemical reactions, transitions between the states of matter, and the mixing of two substances to form a solution

A number of different units are used in heat measurement, e.g., the calorie , the British thermal unit (Btu), and the joule . The apparatus used in heat measurement is called a calorimeter. The measurement given by the most common type of calorimeter depends upon the temperature change in a fixed quantity of water (or some other liquid whose heat capacity is known) when heat is transferred between the water and an exothermic or endothermic process. If the temperature change is not too large, then the heat transferred is equal to the heat capacity of the water times the mass of the water times the change in temperature.

The accuracy of this method of heat measurement depends on the assumption that all the heat transferred in the process passes into or out of the water in which the temperature change is measured, no heat being lost to the environment and none being absorbed by the walls of the container. The amount of heat given off by the combustion of a fuel can be determined very accurately in the so-called bomb calorimeter, which consists of a combustion chamber (the “bombâ€
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