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- Posts: 74
- Joined: Thu May 09, 2019 7:36 pm
Would you be accounting for water content twice if you applied the water content correction factor to a value that has been described on the anhydrous basis already?
For example, I am looking at the USP reference standard Clindamycin Phosphate, and the label indicates "For quantitative applications, determine water content titrimetrically at the time of use, and use a value of 833 ug of clindamycin per mg of material on the anhydrous basis".
If clindamycin already has a value of 833 ug/mg on the anhydrous basis, wouldn't this already account for the water content? Would determining the water content and correcting the 833 ug/mg value using the water content be applying the water correction factor twice?