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Anyone else running this method have similar issues or guidance?
Discussions about GC-MS, LC-MS, LC-FTIR, and other "coupled" analytical techniques.
andrew ryder wrote:
Pretty much what the title says - running 8270 TCLP by SPE (Horizon One Pass, with the in-line carbon cartridge) and pyridine recovery in the blank spikes is abysmal: 4-8% on average, enough to frequently fail even our very forgiving control charts. Interestingly it’s usually a bit better in the MS/MSD, more like 15%. The method suggests that the concentration step may be to blame - we use a Horizon Dryvap system and concentrate the three fractions (acid-base-carbon) in the same reservoir at the lowest heat setting.
Anyone else running this method have similar issues or guidance?
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