by
LALman » Tue Jun 11, 2019 4:40 pm
James_Ball wrote:
Making one from scratch is not a problem, I did all of mine that way. The only one I had a headache with was doing an 8260 Appendix 9 one with over 100 analytes, now that was a headache.
I believe you can run your list full scan then use the AutoSIM in data analysis to get you close, though I usually just do it by hand. For 524 you mainly need SIM for the EDB/DBCP only so that is pretty easy.
Since I run my BTEX-MTBE from the same conditions as my 69 compound 8260. I saved the BTEX version to a new name and used the AutoSIM to convert it. This was successful and I see that resulted in a 40-100% increase in areas and counts. Unfortunately, when I did the same with my 8260 method, it gave an error message about something being <1ms and terminates.
I think this may be due to my habit of including in the 3rd and 4th qualifier ion slots an ion from a nearby peak that might interfere. It makes it easier to see the actual quant ions in context with nearby peaks. But I think AutoSIM sees it as peak overlap. So, I must trim off those extra ions and try that process again.
Also, I am going to trim down my 524 method to only the analytes that my state requires. Its a substantially shorter list.
I don't need SIM for vinyl chloride?
I tried importing this
8260 SIM/SCAN method from Agilent. That crashed my system pretty hard. I had to reboot before my instrument software would come up again. I guess that must be why there is no
http://www.agiilent.com/chem/eMethods website. I was only able to find 3 eMethods on Agilents website. The P&T 8260 eMethod from Agilent #5989-3347EN was the bad actor.